| 7:40 - 8:20 am |
| Grand CB |
Breakfast session - Biocrates |
| Denise Sonntag |
Metabolic Phenotyping in Translational Research |
| Therese Koal |
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| 8:30 - 9:30 am |
| Regency |
Keynote lecture |
| Anne Osbourn |
Harnessing plant metabolic diversity |
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| 10:00 - 11:30 am |
| Regency |
Lung and cardiovascular diseases |
| Stanley Hazen |
Therapeutic approaches targeting gut microbial contribution to cardiometabolic disease |
| Nichole Reisdorph |
Metabolomics in Translational Chronic Obstructive Pulmonary Disease (COPD) Research |
| Philipp Schatz |
Development of a Metabolomics-Based In Vitro Diagnostic for Early Stage Heart Failure and its Translation into a Clinical Test |
| Yasmeen Nkrumah-Elie |
Sphingolipid metabolism is altered in identical twin pairs that are discordant for asthma |
| Dean Jones |
High-resolution metabolomics of cardiovascular disease: Linking health exposures and disease phenotype |
| |
| Grand CB |
Novel use of isotope labels |
| Darren Creek |
Determination of active metabolic pathways in haematopoietic stem cell-derived reticulocytes with stable isotope labelled metabolomics |
| Bernhard Kluger |
A stable isotopic labeling assisted approach for the preparation and LC-HRMS based characterization of plants and filamentous fungi |
| Malcolm McConville |
Dissection of the carbon and energy metabolism of parasitic protozoa using 13C-and 2H-stable isotope resolved metabolomics |
| Christin Zasada |
Quantifying metabolic fluxes in cancer and stem cells |
| Katharina Nöh |
Implementing 13C-Metabolic Flux Analysis in an Industrial Environment: Detailed Intracellular Insights in Penicillin V production with P. chrysogenum |
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| Grand GF |
Data processing |
| Timothy Ebbels |
A Workflow For Processing and Integrating Multi-Cohort, Multi-Platform, Untargeted Metabolomics Data In Large Scale Metabolic Epidemiology: the COMBI-BIO Project |
| Paolo Inglese |
Semi-supervised analysis of 3D mass spectrometry imaging data-sets for tumour heterogeneity exploration |
| Tomáš Pluskal |
Mass Spectrometry Development Kit (MSDK): an open-source Java library for mass spectrometry data processing |
| Andrew Palmer |
Translating molecular information from HR imaging MS data: towards spatial annotation of the cellular metabolome |
| Nazanin Zounemat Kermani |
Spatially resolved metabolomic phenotyping of stromal tissues in breast, colorectal and ovarian cancer by desorption electrospray ionisation mass spectrometry imaging |
| |
| 11:30 am - 12:45 pm |
| Grand CB |
Luncheon - Agilent |
| Theo Sana et al |
Agilent's Metabolomics Showcase Results: How We Did It |
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| Grand GF |
Luncheon - Thermo Scientific |
| Reiko Kiyonami |
Increased throughput, sensitivity and confidence for metabolomics research using an new tribrid Orbitrap mass spectrometer |
| Karl Burgess |
Analytical methodologies for high throughput, robust metabolomics with Orbitrap technology |
| |
| 12:45 - 2:45 pm |
| Grand ADE |
Poster Session 2 |
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compound ID & databases |
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environment & exposure |
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healthy aging |
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metabolic syndrome |
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pathways & microbial metabolism |
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human diseases, infections |
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| 2:45 - 4:15 pm |
| Regency |
Cancer metabolism in human subjects |
| Caroline Johnson |
Correlating Colorectal Cancer with Biofilm Metabolism |
| William Wikoff |
Pre-diagnostic Biomarkers and Clinical Biochemistry of Lung Cancer in Blood and Tumor Tissue |
| Elodie Jobard |
NMR investigation of targeted therapy effects on the host metabolism for HER-2 positive breast cancer |
| Teresa Fan |
Stable Isotope Resolved Metabolomics (SIRM) on Fresh Human Tissue Slices as a Preclinical Drug Testing Platform |
| Ismael Dale |
to be determined |
| |
| Grand CB |
Environmental & human exposure studies |
| Pim Leonards |
An in vivo metabolomic approach for developmental neurotoxic effects by pesticides, combining cognitive and motor function effects with metabolomic pathways |
| Serge Rudaz |
Evaluation and identification of dioxin exposure biomarkers using UHPLC-QTOF, multivariate analysis and in vitro metabolism |
| Sara Tufi |
Exploring surface water extract toxicity and its link to pesticides mixture toxicity in Lymnaea Stagnalis by targeted and untargeted metabolomics |
| Sandra Gouveia-Figueira |
Shifts in Human Lung Lavage and Plasma Lipidome in Response to Biodiesel Exhaust Exposure Investigated by Quantitative Tandem Mass Spectrometry |
| Douglas Walker |
High resolution metabolomics to identify PBB 153 exposure associated metabolic alterations in vivo |
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| Grand GF |
Plant databases and plant systems biology |
| Mark Sumarah |
Discovery of novel antibiotics from fungal endophytes by comprehensive LC-MS based metabolomics |
| Ilana Rogachev |
Advancing Metabolite Identification in Plant Extracts by the Use of a Large-Scale Reference Library |
| Feng Qiu |
Development of Plant Metabolite Annotation Toolbox (PlantMAT) to Increase the Chemical Space and Identification Confidence for Plant Metabolomics |
| Atsushi Fukushima |
Development of metabolite-profiling database in Arabidopsis: AtMetExpress – Meta-analysis of metabolome data |
| Katrin Brauner |
Signal processing as a systems biology tool to uncover diurnal regulation of sink-source interactions based on metabolite profiles |
| |
| 4:45 - 6:15 pm |
| Regency |
Pharmacometabolomics |
| Mohamed Shahin |
Integrating Metabolomics, Transcriptomics, and Genomics Reveals Novel Signatures Associated with Hydrochlorothiazide Blood Pressure Response |
| Balmiki Ray |
Genetic Variation in the Aryl Hydrocarbon Receptor (AHR) Gene and Kynurenine Levels in Major Depressive Disorder: Pharmacometabolomics-Informed Pharmacogenomics |
| Laura M. Yerges |
Genome Wide Association Analysis with Amine Metabolites Reveals Novel Loci Impacting Human Metabolomic Profiles |
| Drew Neavin |
Pharmacometabolomics reveals SOD2 as a tryptophan metabolite ratio regulator associated with selective serotonin reuptake inhibitor response in major depressive disorder. |
| Douglas Kell |
A human metabolic network reconstruction reveals the metabolite-likeness of approved pharmaceutical drugs: a 'rule of 0.5' |
| |
| Grand CB |
Imaging and MS-integration methods |
| Alfredo J. Ibanez |
Benefits and Pitfalls of a single-cell level metabolomics technique: 5 years of Microarrays for Mass Spectrometry |
| Kerem Bingol |
The SUMMIT MS/NMR Method for the Rapid Identification of New Metabolites in Complex Mixtures |
| Alison McGuigan |
TRACER: A novel strategy for assessing metabolomic signatures from cells in 3D heterogeneous microenvironments |
| Basil Nikolau |
Mass Spectrometric Imaging of Plant Metabolites |
| Trent Northen |
Kinetic Mass Spectrometry Imaging |
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| Grand GF |
Pathways and microbial metabolism |
| Uwe Sauer |
Near real-timing metabolome profiling reveals dynamics and regulation of the starvation to growth transition in E. coli |
| Andreas Kühne |
Identification of sites and timings of metabolic regulations from metabolite profiling data using probabilistic graphical modelling |
| Eun Ju Yun |
The first elucidation of the novel metabolic pathway of 3,6-anhydro-L-galactose by integrative analyses of metabolome and transcriptome |
| Sarah Schatschneider |
Metabolic Pathway Profiling of Clostridium autoethanogenum for Sustainable Biofuel Production |
| Yifan Xu |
Toward a comprehensive understanding of cellular metabolism |